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Study on the effect of precise target rTMS on craving and cognitive impairment in alcohol-dependent patients based on MAGNETIC resonance technology

Study on the effect of precise target rTMS on craving and cognitive impairment in alcohol-dependent patients based on MAGNETIC resonance technology

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059763
Enrollment
Unknown
Registered
2022-05-11
Start date
2023-07-01
Completion date
Unknown
Last updated
2024-04-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

alcohol addiction

Interventions

Group 1 :rTMS
Group 2:Pseudo rTMS
Group 3:Routine medication

Sponsors

The Second Affiliated Hospital of Xinxiang Medical College
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. Aged 20-45 years old, right-handed; primary school education or above; 2. Meet the diagnostic criteria for alcohol dependence in the Diagnostic and Statistical Manual of Mental Disorders (DSM-V), and two attending physicians or above are required to independently diagnose; 3. Clinical Institute Withdrawal Assessment-Advanced Revised (CIWA-AR) score < 10; 4. No history of other drug abuse (except tobacco); 5. Fully understand the therapeutic effect of transcranial magnetic therapy and possible adverse reactions during the treatment; 6. Obtain the informed consent of the patient and guardian, and sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Poor treatment compliance; 2. Those with metal foreign bodies built into the skull, those with pacemakers, heart stents, cochlear implants, and those with significantly increased intracranial pressure, etc.; 3. Patients with serious physical diseases such as heart, cerebrovascular, liver, kidney, and hematopoietic system; 4. History of epilepsy and family history of epilepsy.

Design outcomes

Primary

MeasureTime frame
Visual analog craving scale;Hamilton Anxiety Scale, HAMA;Mini Mental State Examination, MMSE;Digit Span Test, DST;Verbal Fluency Test, VFT;Hopkins Verbal Learning Test Revised, HVLT-R;

Secondary

MeasureTime frame
Hamilton Depression Scale, HAMD;

Countries

China

Contacts

Public ContactJiapeng Gu

The Second Affiliated Hospital of Xinxiang Medical College

gjp106242440@126.com+86 13503735832

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026