Cancer
Conditions
Interventions
Group 1:Only immunotherapy
Group 2:Immunotherapy with acupuncture stimulation of Zusanli acupoint
Sponsors
West China Hospital of Sichuan University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients with advanced tumors who are clinically eligible for PD-1 inhibitor therapy and are proposed for PD-1 inhibitor therapy.
Exclusion criteria
Exclusion criteria: 1. Pregnant patients; 2. Patients after organ transplantation; 3. Patients with uncontrolled diabetes mellitus, severe cardiac, central nervous, psychiatric disorders or coagulation disorders; 4. Patients in a state of severe malnutrition; 5. Patients with pacemakers; 6. Patients with bleeding disorders; 7. Patients with a history of severe allergy; 8. Patients with skin infection, breakage, ulcers, scarring at the acupoint of Zusanli; 9. Patients who are allergic to metal or have serious fear of needles and cannot tolerate electroacupuncture treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Disease control rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Objective response rate;Serum dopamine;Serum Norepinephrine;Serum cytokine;Peripheral blood immune cells; | — |
Countries
China
Contacts
Public ContactXuelei Ma
West China Hospital of Sichuan University
Outcome results
None listed