Omicron COVID-19
Conditions
Interventions
Group 1 :YinQiaoSan, One dose daily, divided into two doses in the morning and evening
Group 2:YinQiaoSan and SiNiSan, One dose daily, divided into two doses in the morning and evening
Group 3:Needle burial at acupuncture points (Dazhui, Hegu, Quchi, Waiguan), daily only
Group 4:Orally PF-07321332 100 mg + Paxlovid 300 mg, q12h
Sponsors
Shuguang Hospital Affiliated of Shanghai University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Those who meet the diagnostic criteria for patients with novel coronavirus infection and the criteria for the diagnosis and treatment of TCM exogenous fever emergencies and wind-heat exogenous diseases; 2. Age between 18-85 years; 3. Acute onset, the course of disease is within 5 days; 4. The total number of white blood cells > 3.5 x 10^9 /L and <= 10.0 x 10^9 /L, the absolute value of neutrophils <= 7.0 x 10^9 /L; 5. Informed consent, voluntary subject. The process of obtaining informed consent should comply with GCP regulations; 6. The type of new crown is in accordance with the standard of Diagnosis and Treatment of Novel Coronavirus Pneumonia (Trial Ninth Edition).
Exclusion criteria
Exclusion criteria: 1. Fever caused by other respiratory, digestive, urinary and blood system diseases; 2. Pregnant and lactating women; 3. Patients with serious primary cardiovascular diseases, liver diseases, kidney diseases, hematological diseases and lung diseases or serious diseases affecting their survival are in an unstable period and need active treatment, such as tumors or AIDS; 4. Patients who need hemodialysis or radiotherapy and chemotherapy; 5. Allergic diseases (such as allergic rhinitis, allergic asthma, etc.), or allergies to test drugs, including allergic history to the ingredients of this product, acetaminophen or pharmaceutical excipients; 6. During this course, antiviral drugs have been given before randomization; 7. Unable or unwilling to cooperate with clinical trials due to other diseases; 8. Suspect or have a history of alcohol or drug abuse; 9. Have participated in other clinical trials or are participating in clinical trials of other drugs in the past 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Body temperature;COVID-19 Nucleic Acid Testing; | — |
Countries
China
Contacts
Public ContactOuyang Yang
Shuguang Hospital Affiliated of Shanghai University of Traditional Chinese Medicine
Outcome results
None listed