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Clinical observation on the effect of atomized inhalation local anesthesia on tracheal intubation and extubation

Clinical observation on the effect of atomized inhalation local anesthesia on tracheal intubation and extubation

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059648
Enrollment
Unknown
Registered
2022-05-05
Start date
2022-05-05
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sore throat

Interventions

A group:Each patient in group A is aerosolized with 1% tetracaine 50mg for 15 minutes before surgery
B group:Each patient in group B is aerosolized with 2% lidocaine 200mg for 15 minutes before surgery
C group:Each patient in group C is atomized with 5ml of normal saline for 15 minutes before surgery

Sponsors

Affiliated Hospital of Yan'an University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing tracheal intubation general anesthesia; 2. ASA grade I or II; 3.18 years= age = 65 years; 4. The operation duration is less than 3 hours; 5.BMI:18~28kg/?.

Exclusion criteria

Exclusion criteria: 1. The patient does not cooperate; 2. Patients with severe hypertension and cardio-cerebrovascular diseases; 3. Patients with severe head and face deformities, neck lesions, space occupying lesions of oral cavity and upper respiratory tract, and airway hypersensitivity diseases have cough, pharyngalgia and other symptoms before operation; 4. Malnutrition and myasthenia gravis; 5. People who are allergic to amide and ester local anesthetics; 6. Difficult airway.

Design outcomes

Secondary

MeasureTime frame
Peak pressure, plateau pressure and average airway pressure during mechanical ventilation after endotracheal intubation;Whether there are postoperative pulmonary complications;

Primary

MeasureTime frame
Systolic blood pressure, diastolic blood pressure, mean arterial pressure, pulse oxygen saturation and heart rate were recorded 10 minutes after entering the room, after airway surface anesthesia, when placing laryngoscope, and immediately after endotracheal intubation.;Techanivate score was used to evaluate intubation response;Record whether choking, ventilation and pulse oxygen saturation during extubation.;VAS score was used to record the patient's throat at 0, 4, 12 and 24h after extubation.;

Countries

China

Contacts

Public ContactBaiyanbin

Affiliated Hospital of Yan'an University

1719148711@qq.com+86 13772872354

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026