A prospective study to compare analgesic effect of donated milk, expressed breast milk and glucose for procedural pain in preterm infants

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059635

Enrollment

Unknown

Registered

2022-05-05

Start date

2022-05-06

Completion date

Unknown

Last updated

2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

neonatal procedural pain

Interventions

donated milk group:neonatal infants were given 2ml donated milk before 2 minutes of heel sticks or venipecture

expressed breast milk group:neonatal infants were given 2ml expressed breast milk before 2 minutes of heel sticks or venipecture

glucose group:neonatal infants were given 2ml glucose before 2 minutes of heel sticks or venipecture

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. The gestational age is 26-37 weeks; 2. Body weight < 1500g; 3. Sign the informed consent form for the use of donated breast milk and apply the donated breast milk during hospitalization; 4. The parents of the child sign the informed consent form.

Exclusion criteria

Exclusion criteria: 1.Drug sedation; 2.Severe asphyxia.

Design outcomes

Primary

Measure	Time frame
NIPS pain score;PIPP-R pain score;cry;	—

Secondary

Measure	Time frame
Vital signs;Feeding intolerance;hyperglycemia;	—

Countries

China

Contacts

Public ContactYajing Wang

Peking Union Medical College Hospital

pumcwangyajing@126.com+86 18611740029

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026