Randomized controlled study comparing CGF membrane and Bio-Gide absorbable collagen membrane in Treating Combined Periodontal-endodontic lesions with Palatal Radicular Grooves

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059633

Enrollment

Unknown

Registered

2022-05-05

Start date

2022-10-18

Completion date

Unknown

Last updated

2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Combined Periodontal-endodontic lesions with Palatal Radicular Grooves

Interventions

1:CGF membrane

2: Bio-Gide absorbable bone collagen membrane

Eligibility

Sex/Gender

All

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: 1. The patient is 18 to 45 years old; 2. The patients with lingual sulcus deformity of maxillary incisors have no history of caries and trauma of upper anterior teeth. The X-ray film shows low density shadow in the apical region, accompanied by clinical symptoms, and there is a lingual periodontal pocket caused by an isolated lingual sulcus deformity; 3. Good compliance, able to participate in the follow-up of 12 months after operation; 4. The whole body is in good condition; 5. The patient informed consent and signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Serious systemic diseases (serious hypertension, myocardial infarction, uncontrolled diabetes, hemorrhagic disease, coagulation dysfunction and other blood system diseases, severe asthma, etc.); 2. Severe periodontitis, with extensive alveolar bone absorption in the affected teeth; 3. The tooth root is too short, the crown root ratio is out of balance, and the recovery is poor; 4. Affected teeth with root fracture, apical micro-cracks and root canal perforation; 5. The teeth with incomplete apical foramen; 6. Take drugs that may affect the soft tissue status (such as warfarin and non-steroidal anti-inflammatory drugs) within one month before treatment; 7. During pregnancy, lactation or pregnancy preparation; 8. Those who cannot maintain oral hygiene after operation; 9. Not willing to participate in this study.

Design outcomes

Primary

Measure	Time frame
Periodontal probing depth;X ray;	—

Secondary

Measure	Time frame
SBI;TM;Postoperative pain score;Swelling of the range;	—

Countries

China

Contacts

Public ContactZhang Rui

Ethics Committee of Stomatology School of Wuhan University

29809164@qq.com+86 18986232435

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026