severe pediatric infection
Conditions
Interventions
Gold Standard:Gold standard for pathogen diagnosis: culture or qPCR of sterile specimens.
Index test:pathogen diagnosis and analysis technology based on single molecule sequencing in severe pediatric infection
Sponsors
The Children's Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
No minimum to 18 Years
Inclusion criteria
Inclusion criteria: The following items shall be met: 1. < 18 years old 2. Severe infection, any of the following five items: (1) sepsis, severe sepsis and septic shock (2) severe pneumonia (3) central nervous system infection (4) severe abdominal infection (5) severe cases in major public health emergencies
Exclusion criteria
Exclusion criteria: Compliance with any of the following items is excluded: 1. Unqualified samples: for example, the samples are contaminated, the quantity of samples is insufficient, or the samples are placed for a long time 2. Children who the researchers believe are not suitable to participate in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pathogen detection rate;qPCR;Sensitivity;Specificity;Positive predictive value ;Negative predictive value ; | — |
Countries
China
Contacts
Public ContactQiang Shu
The Children's Hospital, Zhejiang University School of Medicine
Outcome results
None listed