Effect of S-ketamine on the emergence agitation with general anesthesia in pediatric laparoscopic surgery under ERAS mode

Inhibition effect of S-ketamine on the emergence agitation with general anesthesia flowing pediatric laparoscopic surgery under ERAS mode

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059581

Enrollment

Unknown

Registered

2022-05-04

Start date

2022-05-15

Completion date

Unknown

Last updated

2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

indirect inguinal hernia

Interventions

Group S:During anesthesia induction, 0.5mg/kg S-ketamine was administered intravenously

Group N:Equal volume normal saline was injected intravenously during anesthesia induction

Eligibility

Sex/Gender

All

Age

1 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Children with oblique inguinal hernia undergoing internal circumferential suture; 2. Aged 1-7 years; 3. BMI 12-20; 4. ASA grade I-II.

Exclusion criteria

Exclusion criteria: 1. Allergic to esketamine hydrochloride injection; 2. Preoperative liver and kidney dysfunction or heart disease; 3. Symptoms of upper respiratory tract infection within 1 week before surgery; 4. Children with neurological diseases; 5. The operation time is less than 40min.

Design outcomes

Primary

Measure	Time frame
postoperative sedative agitation score;postoperative pain score;	—

Secondary

Measure	Time frame
incidence of propofol injection as a rescue medication;duration of surgery;duration of anesthesia;recovery time;adverse event;	—

Countries

China

Contacts

Public ContactJin Haiyan

jinhaiyan@zju.edu.cn+86 13600538269

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026