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SPECT spleen function imaging and quantitative study

SPECT spleen function imaging and quantitative study

Status
Recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059562
Enrollment
Unknown
Registered
2022-05-04
Start date
2018-12-01
Completion date
Unknown
Last updated
2024-03-18

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypersplenism

Interventions

Gold Standard:The T-A curves of the liver and spleen were obtained by two senior attending physicians who observed each other blindly and independently, and delineated the ROIs of the liver, spleen an
Index test:The part of T-A curve (time is X-axis, radioactivity count is Y-axis) fitted after 5 min was a straight line, and the angle (a angle) between the straight line and the positive half-axis of

Sponsors

The Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Inclusion criteria for healthy control group: healthy subjects without anemia and splenomegaly. 2. Inclusion criteria for the anemia control group: hemorrhagic anemia caused by gastrointestinal bleeding or other reasons, and no splenomegaly, clinically excluded patients with hypersplenism. 3. Inclusion criteria for splenomegaly control group: patients with splenomegaly, but no anemia or other conditions that exclude hypersplenism clinically. 4. Inclusion criteria for the experimental group: patients with significantly reduced pan blood cells and splenomegaly, clinically diagnosed with hypersplenism.

Exclusion criteria

Exclusion criteria: The diagnosis of hypersplenism or other conditions that are not suitable for SPECT examination is not considered clinically.

Design outcomes

Primary

MeasureTime frame
Alpha angle;Specificity;Sensitivity;Area under the curve of the receiver operating characteristic curve;

Countries

China

Contacts

Public ContactPang Xiaoxi

Second Hospital of Anhui Medical University

Frankpang@foxmail.com+86 18101357855

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026