type 2 diabetes combined with mild cognitive impairment (MCI)
Conditions
Interventions
Sponsors
Shenzhen Bao'an District People's Hospital
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Compliance with the diagnosis of T2DM and mild cognitive impairment; 2. Aged >= 60 years; 3. Right-handed; 4. Sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Brain dysfunction caused by neuropsychiatric disorders,alcohol or drug abuse; 2. Combined with serious primary diseases such as diseases in cardiovascular, cerebrovascular, liver, kidney and hematopoietic system; 3. TMS treatment contraindications: pacemaker or cochlear implants, implant device (such as a deep brain stimulator, cereperitoneal shunt) or metal in the brain (such as aneurysm clip); 4. Unable to complete the evaluation, such as serious aphasia, audio-visual disorders, illiteracy, etc.; 5. Taking cognitive-related drugs and participating in other similar research programs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function score; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency spectrum of the resting-state EEG;Brain network connection;Microstate analysis;Daily life ability assessment scale;Incubation period of auditory evoked potential P300;Amplitude of auditory evoked potential P300; | — |
Countries
China
Contacts
Public ContactWang Dan
Shenzhen Bao'an District People's Hospital
Outcome results
None listed