gastrointestinal cancer
Conditions
Interventions
Group C1:Add 5mg/kg calcium gluconate injections
Group C2:Add 10mg/kg calcium gluconate injections
Group C3:Add 20mg/kg calcium gluconate injections
Sponsors
Department of Anesthesiology, Affiliated Hospital of Xuzhou Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 65 years; 2. ASA grade I~III; 3. Elderly patients undergoing laparoscopic surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Predict difficult airway; 2. BMI >30kg/m^2; 3. Previous asthma, chronic obstructive pulmonary disease, acute lung injury or acute respiratory distress syndrome within 1 month before surgery; 4. Severe liver or kidney disease; 5. Complicated with neuromuscular diseases, recent use of drugs that affect the duration and intensity of neuromuscular block drugs; 6. Hypercalcemia, hyperkalemia, hyperhypomagnesemia; 7. History of malignant hyperthermia; 8. Neostigmine, atropine and calcium were contraindicated; 9. Electrolyte and metabolic balance disorders; 10. Intraoperative blood transfusion; 11. Hypoproteinemia or presence of endocrine diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| time of TOFr>=0.90; | — |
Secondary
| Measure | Time frame |
|---|---|
| incidence of hypoxemia;TOFr values;incidence of complications (airway obstruction) corresponding to residual muscle relaxations;time of extubation;time of get out of PACU;blood calcium concentration;signs and symptoms associated with muscle strength recovery;the incidence of postoperative pulmonary complications; | — |
Countries
China
Contacts
Public ContactYan Ming
Affiliated Hospital of Xuzhou Medical University
Outcome results
None listed