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A double-blind controlled study on the efficacy of probiotics in adjuvant treatment of influenza

A double-blind controlled study on the efficacy of probiotics in adjuvant treatment of influenza

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059514
Enrollment
Unknown
Registered
2022-05-03
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Influenza

Interventions

Group 1:Receive a single probiotic CCFM1026 supplement
Group 2:A compound probiotic (CCFM1026+GL-104+MP108) was administered
Group 3:Take placebo

Sponsors

Affiliated Hospital of Jiangnan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged over 18 years. 2. The patient was clinically diagnosed with influenza virus infection. 3. Can cooperate with the collection of experimental specimens and regular callback. 4. Patient or family member has signed subject consent form.

Exclusion criteria

Exclusion criteria: 1. The patient was first diagnosed as having other serious diseases combined with influenza. 2. Congenital intestinal abnormalities, such as Hirschsprung's disease or intestinalatresia, are appraised by physicians as not appropriate to be added to this clinical trial. 3. Other gastrointestinal diseases with symptoms of intestinal inflammation and increased permeability. 4. Patients who have taken immunosuppressive drugs, steroids, various antibiotics and Tcell inhibitor ointment within 4 weeks. 5. The patient has consumed probiotic-related products (powder, yogurt, yogurt, or other fermented foods) on a continuous basis (for five or more consecutive days) within the last 1 month. 6. Use nasal spray five or more days a week, systemic steroids, testosterone, or high-dose anti-inflammatory drugs (e.g., aspirin greater than 600 mg/day) for those who have participated in other clinical trials and are on trial drugs within the last 1 month. 7. No probiotics were taken for more than 10 days during the trial. 8. Patients who plan to change their rhinitis medication in the short term. 9. Others who were assessed by physicians as unfit to enter the trial.

Design outcomes

Primary

MeasureTime frame
height;fecal NGS analysis;IgG;IL-6;IL-8;IgA;weight;body mass index;blood pressure;temperature;pulse;

Countries

China

Contacts

Public ContactLu Wenwei
luwenwei@jiangnan.edu.cn+86 18762691080

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026