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Protein profiling of exosomes from peripheral blood sources in patients with coronary heart disease

Protein profiling of exosomes from peripheral blood sources in patients with coronary heart disease

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059496
Enrollment
Unknown
Registered
2022-05-02
Start date
2022-05-03
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

coronary heart disease

Interventions

Group 1 :
Group 2:

Sponsors

Guang’anmen Hospital, China Academy of Chinese Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for coronary heart disease; 2. Meet the diagnostic criteria for healthy people; 3. Age between 30-80 years old, male or female; 4. Voluntarily participate and sign the informed consent; 5. Those who meet conditions 1, 3, and 4 are included in the coronary heart disease group; those who meet conditions 2, 3, and 4 are included in the normal control group.

Exclusion criteria

Exclusion criteria: 1. Patients with congenital heart disease, cardiomyopathy, valvular heart disease, and severe arrhythmia; 2. Severe neurosis, menopausal syndrome, hyperthyroidism, cervical spondylosis, biliary heart disease, and chest pain caused by gastroesophageal reflux; 3. Severe cardiovascular and cerebrovascular complications; 4. Poorly controlled hypertension, SBP >= 180 mmHg, DBP >= 120 mmHg; 5. Severe liver and kidney insufficiency; 6. Acute infection within two weeks, fever or recent use of anti-inflammatory drugs; 7. Pregnant or lactating women; 8. Severe allergic diseases, autoimmune diseases, severe systemic malnutrition, malignant tumors, mental diseases; 9. Those who refuse to sign the informed consent.

Design outcomes

Primary

MeasureTime frame
Exosome protein profile;

Countries

China

Contacts

Public ContactYuanhui Hu

Guang’anmen Hospital, China Academy of Chinese Medical Sciences

huiyuhui55@sohu.com+86 13911386285

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026