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Feasibility clinical study of embryo evaluation in IVF/ICSI population using noninvasive chromosomal screening (NICS) technique

Feasibility clinical study of embryo evaluation in IVF/ICSI population using noninvasive chromosomal screening (NICS) technique

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059490
Enrollment
Unknown
Registered
2022-05-02
Start date
2022-06-01
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

None listed

Sponsors

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. For patients with remaining frozen embryos: (1) IVF/ICSI fertilized patients; (2) There are D5 remaining frozen embryos; (3) Agree to single blastocyst transfer; 2. For new cycle patients, patients receive transplantation according to morphological standards for the first time: (1) IVF/ICSI fertilized patients; (2) Agree to raise all capsules in this cycle; (3) Agree to single blastocyst transfer; 3. For patients newly admitted to the cycle, patients receive transplantation according to "NICS+ morphology "criteria for the first time: (1) IVF/ICSI fertilized patients; (2) The woman is >= 35 years old or has a history of miscarriage or implant failure; (3) The number of blastocysts >= 3.

Exclusion criteria

Exclusion criteria: 1. Patients with chromosomal abnormalities/single gene genetic diseases; 2. Uterine lesions that may affect implantation (including history of intrauterine adhesions, submucosal fibroids, muscle wall > 4 cm and interendometrial fibroids, adenomyosis); 3. Those with hydrosalpinx and no proximal tubal ligation; 4. Uterine malformation; 5. Severe endocrine diseases; 6. Any situation that other researchers think is not suitable for participating in this study.

Design outcomes

Primary

MeasureTime frame
Ongoing pregnancy rate;

Secondary

MeasureTime frame
Clinical pregnancy rate;Miscarriage rate;

Countries

China

Contacts

Public ContactJunzhao Zhao

The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University

z.joyce08@163.com+86 13806890385

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026