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Dynamic magnetic resonance imaging study of regional brain nerve activity and functional connectivity in patients with alcohol dependence

Dynamic magnetic resonance imaging study of regional brain nerve activity and functional connectivity in patients with alcohol dependence

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059483
Enrollment
Unknown
Registered
2022-05-01
Start date
2022-05-16
Completion date
Unknown
Last updated
2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol dependence

Interventions

Group 1 :
Group 2:

Sponsors

The Second Affiliated Hospital of Xinxiang Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. At the same time meet the diagnostic criteria for alcohol dependence in DSM-V of the fifth edition of the American Diagnostic and Statistical Manual of Mental Disorders and ICD-10 of the International Classification of Diseases Tenth Edition, and have been diagnosed by a third-level physician after ward rounds; 2. Male, aged between 18-60; 3. Right-handed, have at least 6 years of education, and the intelligence is within the normal range as assessed by the competent physician; 4. Has stopped drinking alcohol for more than 2 weeks, and is currently not using benzodiazepines and sedative drugs; 5. No history of other psychoactive substance use (except smoking).

Exclusion criteria

Exclusion criteria: 1. Have a family history of psychotic symptoms or mental disorders; 2. Have a history of dependence on other psychoactive substances (except smoking); 3. Can not tolerate magnetic resonance examination; 4. Subjects with a translation > 3 mm or a rotation > 3°during the fMRI examination of the head; 5. There is a history of traumatic brain injury or coma in the past.

Design outcomes

Primary

MeasureTime frame
dynamic amplitude of low-frequency fluctuation;dynamic functional connectivity;

Countries

China

Contacts

Public ContactGao Yan

The Second Affiliated Hospital of Xinxiang Medical University

2582189898@qq.com+86 13140591451

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026