Electro-acupuncture regulate immune function in patients with sepsis via PD-1 and other pathways

Electro-acupuncture at Zusanli, Qihai, and Guanyuan acupoints regulate immune function in patients with sepsis via PD-1 and other pathways

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059459

Enrollment

Unknown

Registered

2022-04-30

Start date

2019-07-09

Completion date

Unknown

Last updated

2024-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sepsis

Interventions

Group 1:Electro-acupuncture

Group 2:Western medicine

Eligibility

Sex/Gender

All

Age

18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Age 18-85 years; 2. Diagnosis of sepsis; 3. Signed the informed consent form.

Exclusion criteria

Exclusion criteria: 1. Pregnancy or psychiatric disorder; 2. Immune deficiency or using immunosuppressants or immune enhancers; 3. HIV-ab positive; 4. Unwilling to participate in the study or cooperate with the treatment.

Design outcomes

Primary

Measure	Time frame
Blood routine;Levels of tumor necrosis factor-a;C-reactive protein (CRP);Acute Physiology and Chronic Health Evaluation-? (APACHE-?);Sequential Organ Failure Assessment (SOFA) scores;	—

Secondary

Measure	Time frame
T lymphocyte subsets;NK cells;serum PD-1;The patient's condition at 28 days;Intestinal flora;	—

Countries

China

Contacts

Public ContactYang Guang

The Second Affiliated Hospital of Guangzhou University of Chinese Medicine

yangguang@gzucm.edu.cn+86 13580421600

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026