Estimation of the ED50 of propofol with intravenous lidocaine for inserting gastrointestinal endoscope without body movement in patients under the age of 50

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059450

Enrollment

Unknown

Registered

2022-04-29

Start date

2022-05-18

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

painless gastrointestinal endoscopy

Interventions

Control group:propofol

Experimental group:lidocaine

Eligibility

Sex/Gender

All

Age

18 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-50 years who underwent painless gastroscopy according to ASA grade I-II in our hospital; 2. BMI 50 beats/min and no previous atrioventricular block; 5. Good liver and kidney function; 6. Non-pregnant or lactating patients.

Exclusion criteria

Exclusion criteria: 1. Patients who cannot obtain informed consent; 2. Patients with allergic history to lidocaine; 3. Nervous system and severe mental illness; 4. Patients who have taken oral analgesic, hypnotic and antidepressant drugs in recent 7 days.

Design outcomes

Primary

Measure	Time frame
Propofol dose;	—

Secondary

Measure	Time frame
Time to add propofol firstly;	—

Countries

China

Contacts

Public ContactAn Lixin

Beijing Friendship Hospital Affiliated to Capital Medical University

anlixin8120@163.com+86 10 63138360

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 13, 2026