Effect and mechanism of percutaneous auricular vagus nerve stimulation on peripheral autonomic nerve function in patients with heart failure and insomnia

Status

Recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059439

Enrollment

Unknown

Registered

2022-04-29

Start date

2022-04-21

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Heart failure with insomnia

Interventions

Group 1 :percutaneous ear vagus nerve stimulation

Group 2:percutaneous ear vagus nerve sham stimulation group

Eligibility

Sex/Gender

All

Age

45 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age: 45-80 years old; 2. Patients with systolic heart failure; 3. NYHA is classified as Grade II or III; 4. LVEF <= 50% 5. Insomnia symptoms last for more than 3 months, 3 times or more per week.

Exclusion criteria

Exclusion criteria: 1. Acute heart failure; 2. Patients with chronic heart failure accompanied by acute hemodynamic disorder or acute decompensation; 3. Patients diagnosed with depression and other mental diseases; 4. Exclude other sleep-related diseases (OSA, etc.).

Design outcomes

Primary

Measure	Time frame
Polysomnia monitoring;	—

Countries

China

Contacts

Public ContactSizhi Ai

The First Affiliated Hospital of Xinxiang Medical College

ai5542591@163.com+86 18625960670

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026