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Epigenetic mechanism of bipolar disorder

Epigenetic mechanism of bipolar disorder

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059426
Enrollment
Unknown
Registered
2022-04-29
Start date
2022-08-01
Completion date
Unknown
Last updated
2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bipolar disorder

Interventions

Group 1 :
Group 2:

Sponsors

The First Hospital of Hebei Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
14 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Inpatients who meet the DSM-V diagnostic criteria for depression/mania episodes, either first episode or relapse; 2. Age 14-65 years old, gender is not limited; 3. Han nationality; 4. Hamilton Depression Scale (24 items) >= 17 points, Young's Mania Scale = 12 points; 5. Have certain reading and writing skills, and be able to complete questionnaires and psychological assessments; 6. Right-handed; 7. The patient himself signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Those who suffer from other DSM-V axis I, axis II mental disorders or other diseases or have epilepsy or cognitive impairment; 2. Combined with serious physical diseases or organic diseases in the brain; 3. Pregnant or lactating women; 4. Malnourished or obese (BMI = 30); 5. Substance dependence such as drugs and alcohol; 6. Accompanied by severe sleep disorders, such as sleep apnea, restless legs, etc.

Design outcomes

Primary

MeasureTime frame
DNA Methylation;

Countries

China

Contacts

Public ContactWang Yumei

The First Hospital of Hebei Medical University

wangyumei19771021@hotmail.com+86 18633889983

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026