Benign symptomatic nodule of thyroid
Conditions
Interventions
Microwave ablation group:Microwave Ablation for Benign Thyroid Nodules
Surgery group:Surgery for Benign Thyroid Nodules
Sponsors
Beijing Friendship Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Ultrasound examination revealed a single thyroid nodule in BI-RADS 3-4a category, basically excluding thyroiditis and thyroid malignancy, and repeat FNA confirmed it as a benign nodule; 2. The patient has subjective symptoms related to the nodule, such as neck discomfort or pain, compression (dysphagia, dyspnea), foreign body sensation, etc.; 3. Enlarged nodules affect beauty; 4. Benign thyroid nodules grow rapidly to obvious enlargement (> 4 cm) and have compression symptoms or clinical needs; 5. Heart, lung, brain, kidney and coagulation system diseases without anesthesia and surgical contraindications.
Exclusion criteria
Exclusion criteria: 1. Thyroid nodules combined with hyperthyroidism; 2. Others who cannot tolerate conventional anesthesia and surgical treatment; 3. Severe coagulation dysfunction; 4. Ultrasound examination showed that the thyroid nodule was located retrosternally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Thyroid nodule volume reduction rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Treatment success rate;Serum thyroid hormone levels;Hamilton Anxiety Scale, HAMA;Patient's clinical symptom;Beauty rating;Surgical complication;Economic expenditure;Patient quality of life; | — |
Countries
China
Contacts
Public ContactLinxue Qian
Beijing Friendship Hospital, Capital Medical University
Outcome results
None listed