Heart valve disease
Conditions
Interventions
Ciprofol Group:Ciprofol induction
Sponsors
Beijing Anzhen Hospital Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients with valvular disease undergoing elective valve surgery; 2. Age 18 and above; 3. New York Heart Association cardiac function grade II or III, left ventricular ejection fraction (LVEF) >= 45%; 4. ASA grade II-III; 5. Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Combined with other cardiovascular diseases (patients with severe hypertension, grade III or above, who are not eligible for elective surgery); 2. Complicated with serious respiratory diseases (such as chronic bronchitis, emphysema, decreased pulmonary function and pulmonary functional injury caused by other reasons); 3. Complicated with serious diseases of the urinary system; 4. Moderate and severe hepatic and renal insufficiency; 5. Complicated with serious mental diseases (such as schizophrenia, mania and depression); 6. BMI>30kg/m2; 7. Severely difficult airway (grade III or IV of modified Mahalanobis score); 8. Impaired motor language function cannot cooperate with the assessment; 9. History of allergy to narcotic drugs (including those allergic to propofol or cyclophenol injection excipients: soybean oil, glycerol, egg yolk lecithin and other components) history of anesthesia accidents.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of post-induction hypotension; | — |
Secondary
| Measure | Time frame |
|---|---|
| Use of norepinephrine;Cardiac index;Cardiac output;Stroke volume;Stroke volume index;Systemic vascular resistance;Systemic vascular resistance index; | — |
Countries
China
Contacts
Public ContactJun Ma
Beijing Anzhen Hospital, Capital Medical University
Outcome results
None listed