Multivessel coronary artery disease
Conditions
Interventions
Intervention group:2-staged hybrid coronary revascularization
Control group:Percutaneous coronary intervention
Sponsors
Liaocheng City Heart Disease Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age >=18 years; 2. Clinical indication for coronary revascularization: (1) Two-vessel disease with LAD and/or three-vessel disease with SYNTAX score 1.5 mm ) to require revascularization, it is regarded as a two-vessel disease; (2) If there is no LAD, the diagonal branch replaces the function of the LAD, and the diagonal branch is regarded as an anterior Descending treatment; 3. Signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Left main disease, single branch disease, double branch disease without LAD; 2. Prior PCI and/or intrastent restenosis; 3. Patients with any form of cardiac surgery and severe pleural adhesion in the past; 4. Acute myocardial infarction, preoperative cardiogenic shock, hemodynamic instability; 5. Fresh coronary thrombosis; 6. The LAD has severe muscle bridge and complicated coronary artery anatomy, so it is unsuitable for CABG or PCI without LAD. 7. Chronic occlusion of LAD or >=2 other coronary Ctos capable of revascularization; 8. Other cardiac surgery (including but not limited to valvular surgery, aortic resection, and left ventricular aneurysm resection) is planned during hospitalization; 9. Acute heart failure within 30 days, EF 12 months; 11. Severe lung disease, unable to tolerate single lung ventilation; 12. Severe obesity (BMI > 40); 13. Patients who cannot be evaluated after 1 year and cannot be followed up within 1 year at the discretion of the investigator; 14. Mental abnormality can not cooperate; Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Major adverse cardiac and cerebrovascular event; | — |
Secondary
| Measure | Time frame |
|---|---|
| Overall or individual incidence of major unconscionable cerebrovascular events (MACCE);Recurrent angina pectoris after surgery;Postoperative arrhythmia;Patency rate of left internal mammary artery and drug-eluting stents at 1 year;5-year survival rate; | — |
Countries
China
Contacts
Public ContactDapeng Yu
Liaocheng City Heart Disease Hospital
Outcome results
None listed