Effect of Intraoperative Dextrose Infusion for Prevention of Postoperative Nausea and Vomiting in thyroidectomy: A Single Center Double-Blind Randomized Clinical Study

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059370

Enrollment

Unknown

Registered

2022-04-28

Start date

2022-04-15

Completion date

Unknown

Last updated

2024-03-04

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thyroidectomy

Interventions

Trial group:Intraoperative Ringer's Solution with 5% Dextrose Infusion in thyroidectomy 10ml/kg/h

Control group:Intraoperative Ringer's Solution with same volume normal saline Infusion in thyroidectomy 10ml/kg/h

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: 1. Age 18 to 65 years old; 2. American Association of Anesthesiologists (ASA) grade is I ; 3. All of the patients proposed to perform thyroidectomy; 4. The patients volunteered to participate in this trial and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Type I or Type II diabetes patients; 2. Fasting glucose of more than 7.0mmol/L or glycosylated hemoglobin of more than 6.5%; 3. Gastric emptying dysfunction including gastroesophageal reflux disease; 4. Receive antiemetic drug 24h before thyroidectomy; 5. Patient has a history of postoperative nausea and vomiting; 6. Patient with motion sickness.

Design outcomes

Primary

Measure	Time frame
Incidence of Postoperative Nausea and Vomiting;	—

Secondary

Measure	Time frame
Occurrence degree of nausea and vomiting;Time of the first request for antiemetic;Total dosage of antiemetic 24h after surgery;	—

Countries

China

Contacts

Public ContactTao Luo

Peking University Shenzhen Hospital

496855048@qq.com+86 13510820779

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026