Infertility
Conditions
Interventions
Sponsors
Chongqing Health Center for Women and Children
Eligibility
Sex/Gender
Female
Age
25 Years to 36 Years
Inclusion criteria
Inclusion criteria: 1. The woman is 25-36 years old; 2. BMI 18-25 kg/m2; 3. Repeated implantation failure for unknown reasons (those who have undergone 3 or more embryo transfers or have accumulated more than 4 embryos without clinical pregnancy and have no clear reasons for implantation failure); 4. Transplantable frozen blastocysts (>=3BB); 5. Estrogen progesterone replacement therapy (HRT), endometrial thickness >=7mm on endometrial transformation day.
Exclusion criteria
Exclusion criteria: 1. Chromosomal abnormalities of both male and female (excluding chromosomal polymorphism); 2. Patients with PGT; 3. Uterine lesions that may affect implantation (including history of intrauterine adhesion, submucosal myoma, intramural myoma > 4cm, adenomyosis); 4. Hydrosalpinx without proximal tubal ligation; 5. Uterine malformation; 6. Repeated spontaneous abortion (2 or more fetal loss before 28 weeks of gestation); 7. Patients with implant failure due to known embryonic factors; 8. Serious internal and external secretory diseases; 9. Any circumstances deemed unsuitable for participation in this study by other researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rate of intrauterine embryo implantation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Intrauterine clinical pregnancy rate;Continued pregnancy rate;Incidence of ectopic pregnancy;Spontaneous abortion rate (less than 12 weeks); | — |
Countries
China
Contacts
Public ContactHuang Guoning
Chongqing Health Center for Women and Children
Outcome results
None listed