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Investigation of the relationship between subgingival microbial diversity, gingival sulcus fluid composition, and periodontal probing depth.

Investigation of relationship between site-specific microbiota composition and local periodontal status

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059339
Enrollment
Unknown
Registered
2022-04-28
Start date
2022-04-28
Completion date
Unknown
Last updated
2024-02-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontal disease

Interventions

Sponsors

West China Hospital of Stomatology Sichuan University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. 18-65 years old, male or female; 2. Periodontally healthy, gingivitis patients and periodontitis patients; 3. In Good general health condition; 4. No active caries; 5. Sign the informed consent form and be able to complete the test as required.

Exclusion criteria

Exclusion criteria: 1. Patients with systemic diseases; 2. Pregnant or women with pregnancy plans within 1 year; 3. Wearing orthodontic brackets or orthodontic appliances; 4. Wearing removable denture or gross prosthesis; 5. Suffering from untreated dental caries, mucosal lesions, soft and hard tissue tumors, and other oral diseases other than periodontal disease; 6. Received periodontal treatment or surgery within 3 months; 7. Smoke cigarettes, any e-cigarette products, pipes or cigars; 8. Use antibiotic mouthwash antibacterial efficacy toothpaste Within 3 months; 9. Have taken drugs that cause gingival hyperplasia within 3 months; 10. Have taken antibiotics, antiviral antifungal antiparasitic steroids, or immunomodulatory drugs probiotic preparations (excluding fermented foods such as yogurt)through oral intravenous, injection or inhalation within 3 months.

Design outcomes

Primary

MeasureTime frame
Probe depth;Bleeding on probing;Tooth Mobility;Gingival recession;Attachment loss;

Secondary

MeasureTime frame
Plaque index;Gingival index;

Countries

China

Contacts

Public ContactRan Cheng

West China School of Stomatology, Sichuan University

chengran@scu.edu.cn+86 13880626991

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026