Atelectasis
Conditions
Interventions
Driven pressure group:After mechanical ventilation, PEEP was titrated with driving pressure to find the corresponding PEEP value of the lowest driving pressure, and the optimal PEEP was maintained int
Control group:After mechanical ventilation, PEEP value was adjusted to 5cmH2O according to lung protection ventilation strategy
Sponsors
Guangdong Provincial Hospital of Tradition Chinese Medicine
Eligibility
Sex/Gender
All
Age
75 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for spinal surgery under general anesthesia with endotracheal intubation; 2. ASA grade I~III; 3. Age 75-85; 4. Operation time less than 4 hours; 5. Those who voluntarily participate in the study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with severe lung diseases, such as chronic obstructive pulmonary disease, pleural effusion, asthma, pneumothorax, previous chest surgery, such as lobectomy, etc.; 2. Severe cardiovascular diseases and liver and kidney dysfunction; 3. BMI>= 30 kg/m2; 4. Preoperative oxygen saturation <=90%; 5. Participants in other clinical trials within 3 months prior to study inclusion.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lung ultrasound score;Incidence of actelectasis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygenation index;Intrapulmonary shunt volume;Incidence of postoperative lung complications;Intraoperative fluid replacement amount; | — |
Countries
China
Contacts
Public ContactJinhe Deng
Guangdong Provincial Hospital of Tradition Chinese Medicine
Outcome results
None listed