Mild cognitive impariment
Conditions
Interventions
Sponsors
Rehabilitation Industry Institute of Fujian University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
50 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria of MCI; 2. The score of Montreal Cognitive Assessment scale(MoCA) less than 26, and if the years of education were less than 12 years, the score should be added 1 score; 3. The score of Activity of Daily Living Scale(ADL) less than 22; 4. Meet the level of global deteriorate scale 2-3; 5. Aged 50 to 75 years; 6. Not engaged in regular exercise in the last six months (regular exercise means exercise with a frequency of at least three times a week and at least 20 min per session); 7. No contraindications of MRI and tDCS; 8. The Participants had informed consent and participated voluntarily.
Exclusion criteria
Exclusion criteria: 1. Patients with cognitive impairment caused by depression,the depression patients with score of GDS-15 more than or equal 9; 2. Patients with cognitive impairment caused by taking drugs (antipsychotics; benzodiazepines, etc.), poisoning and other reasons; 3. Patients with uncontrollable blood pressure (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100 mmHg after medication); 4. Participants cannot cooperate to complete the exercise program, such as motor dysfunction caused by nervous system diseases (stroke, Parkinson's disease), musculoskeletal system diseases (lower limb arthritis, history of hip and knee replacement, etc.), serious organ diseases and other exercise contraindications; 5. Participants cannot complete the index evaluation, such as severe aphasia, audio-visual impairment, illiteracy, etc; 6. Participants in other research trials that are participating in and influencing the results of this study; 7. Taking any medications in the past 6 months which may cause impaired or improved cognitive performance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Wechsler Memory Scale, Chinese Version; | — |
Secondary
| Measure | Time frame |
|---|---|
| Auditory verbal learning test, AVLT;The Rey-Osterrieth complex figure test (ROCF); | — |
Countries
China
Contacts
Public ContactXu Ying
College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine
Outcome results
None listed