Evaluation of the effectiveness and persistence of immune effects after COVID-19 vaccination
Conditions
Interventions
Experimental group:None
Sponsors
Zhuhai People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The age is between 18 and 59; 2. Two inoculations of domestic COVID-19 inactivated vaccine have been completed, and the interval between the second dose of vaccine is more than 6 months; 3. Good compliance and voluntary signing of informed consent.
Exclusion criteria
Exclusion criteria: 1. The history of novel coronavirus infection; 2. Have a history of allergy to drugs or vaccines; 3. Respiratory symptoms such as fever, runny nose and cough have occurred in the past 7 days; 4. There has been a history of high and medium risk areas or overseas living in the past 14 days; 5. Vaccination history of other types of COVID-19 vaccines except domestic inactivated COVID-19 vaccines; 6. Patients with cardiovascular and cerebrovascular diseases, malignant tumors, gastrointestinal diseases, acute and chronic kidney diseases, infectious diseases or serious mental and neurological diseases; 7. Patients with immune deficiency or immunosuppression treatment; 8. Being involved in other COVID-19 related clinical trials or other drug clinical trials; 9. According to the judgment of the researcher, the subject has any other factors that are not suitable for the clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum neutralizing antibody titer and immune level; | — |
Countries
China
Contacts
Public ContactMeixiao Zhan
Zhuhai People's Hospital
Outcome results
None listed