Ischemic Stroke
Conditions
Interventions
Invalid recanalization group:None
Effective recanalization group:None
Sponsors
Affiliated Dongguan Hospital, Southern Medical University(Dongguan People's Hospital)
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. The diagnosis of acute ischemic stroke conforms to the diagnostic criteria of the Chinese Guidelines for the Diagnosis and Treatment of Acute Ischemic Stroke 2018, and has been confirmed by brain MRI; 2. 18-85 years; 3. Endovascular treatment (EVT) of the anterior circulation can be extended to 24 hours after the onset of the disease within 6 hours after the onset of the disease; 4. Under the guidance of imaging, the age is greater than 80 years old, the NIHSS score is greater than 10 points, the infarct core is not greater than 21 mL, or the age is less than 80 years old, the NIHSS score is greater than 10 points but not greater than 20 points, the infarct core is not greater than 31 mL, or the age is less than 80 years old, the NIHSS score is greater than 20 points, the infarct core is not greater than 51 mL, which meets the DAWN study inclusion criteria, and the treatment time window is extended to 24 hours; 5. Occlusive vessels include: common carotid artery (CCA), internal carotid artery (ICA), middle cerebral artery (MCA) M1 and M2 segments, anterior cerebral artery (ACA) A1 segment, basal artery (BA), vertebral artery (VA), posterior cerebral artery P1 segment occlusion.
Exclusion criteria
Exclusion criteria: 1. Those with severe physical diseases and other brain organic diseases who cannot cooperate; 2. Any mental disorder, personality disorder or abuse or dependence of psychoactive substances; 3. Take probiotics drugs or drinks regularly in the past month; 4. Antibiotics have been used in the past three months; 5. Severe diarrhea in the past 3 months (watery stool 3 or more times a day and lasting for 3 or more days); 6. Severe constipation in the past 3 months (defecation twice or less per week, accompanied by difficulty in defecation); 7. Women during menstruation, pregnancy and lactation; 8. AIS patients with mechanical embolectomy failure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MRs score at 90 days; | — |
Countries
China
Contacts
Public ContactLin Weifeng
Affiliated Dongguan Hospital, Southern Medical University(Dongguan People's Hospital)
Outcome results
None listed