Climacteric syndrome
Conditions
Interventions
Probiotic1- intervented group:Probiotic1
Probiotic2- intervented group:Probiotic2
Placebo group:Placebo
Sponsors
The People's Hospital of Xishan, Wuxi
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1. Perimenopausal female patients aged 40-60 years; 2. Kupperman score table>6 points or any single score = 2 points; 3. Serum hormone level: FSH = 30IU/L; 4. Have certain communication skills; 5. Those who are willing to intervene with lactic acid bacteria; 6. Understand and sign relevant informed consent.
Exclusion criteria
Exclusion criteria: 1. Known or suspected breast cancer, known or suspected sex hormone dependent malignant tumor, blood disease, liver and kidney dysfunction disease, thrombophlebitis; 2. Patients with coronary heart disease, angina pectoris, hypertensive crisis and other serious basic diseases; 3. People with previous gonad-related endocrine diseases; 4. Persons with previous mental illness; 5. Patients who need to take antibiotics during treatment; 6. Those who have taken estrogen and estrogen-like supplements in the past three months; 7. The doctor in charge of clinical research believes that there are other circumstances that are not suitable for participating in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Kupperman Score;MENQOL; | — |
Countries
China
Contacts
Public ContactWang Haojue
Jiangnan University
Outcome results
None listed