Effect of dexmedetomidine on postoperative nausea and vomiting in patients undergoing gynecological laparoscopic surgery

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059210

Enrollment

Unknown

Registered

2022-04-27

Start date

2022-04-25

Completion date

Unknown

Last updated

2024-02-19

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative nausea and vomiting

Interventions

Dexmedetomidine group(Dex group):Receiving a dose of dexmedetomidine

Control group(Ctrl group):Receiving 4 mg of ondansetron

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.The inclusion criteria are adult female patients(age between 18 and 65 years old) who are scheduled to undergo elective gynecological laparoscopic surgery.

Exclusion criteria

Exclusion criteria: 1. The patient's ASA anesthesia grade = grade III; 2. History of smoking and brain injury; 3. Poor control of hypertension, atrioventricular block = ? degree, obesity (BMI>30 kg/m2); 4. Pregnancy or breastfeeding period; 5. Known allergy to drugs used in the study protocol, history of motion sickness, and history of gastrointestinal surgery; 6. Liver and kidney dysfunction (liver enzyme or creatinine is 1.5 times higher than the normal value), alcoholism or drug abuse, mental illness, use of antiemetics, opioids, psychotropic drugs, glucocorticoids 24 hours before surgery; 7. The patient participated in other studies.

Design outcomes

Primary

Measure	Time frame
The incidence of 24-h postoperative nausea and vomiting;	—

Countries

China

Contacts

Public ContactDing lin

Hospital of Traditional Chinese Medicine of Liaocheng City

dinglin313@aliyun.com+86 18361273853

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026