Major depression disorder
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Meet the DSM-V clinical diagnostic criteria for depression; 2. Hamilton depression score should be greater than or equal to 18 points; 3. Aged >=18 years; 4. Patients with first-time depression who have not taken any other antidepressants; 5. Able to understand and cooperate with the completion of scale assessment.
Exclusion criteria
Exclusion criteria: 1. Patients with other mental diseases or previous mental diseases; 2. Previous organic brain lesions or severe external injuries to the brain; 3. Patients with severe heart, liver and kidney insufficiency, metabolic diseases and other serious physical diseases; 4. Pregnant or lactating patients; 5. Have taken or used antibiotics (or) microecological regulators continuously within the past month; 6. Abnormal laboratory routine examination (such as liver function, blood routine and urine routine); 7. Participated in another clinical study within 3 months; 8. Patients with serious suicidal tendencies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intestinal flora;Inflammatory factor; | — |
Countries
China
Contacts
Wuxi Mental Health Center