cerebral hemorrhage
Conditions
Interventions
Experimental group:Acupuncture + rehabilitation + Western medical treatment
Healthy control group:NA
Sponsors
Shenzhen Hospital of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria for patients with cerebral hemorrhage: (1) Meet the diagnostic criteria for hemorrhagic stroke; (2) The clinical stages of hemorrhagic apoplexy were convalescent stage and sequelae stage; (3) Unilateral limb movement disorders, including upper limb or lower limb movement disorders, without ataxia; (4) Clear consciousness, can cooperate with the completion of scale evaluation, magnetic resonance examination and acupuncture comprehensive treatment; (5) Aged between 18 and 80 years, no gender limit; (6) The subjects with hemorrhagic stroke were mild or moderate, that is, the NIHSS score was within the range of 1-20 points; (7) Normal cognitive function, MMSE>=18 points (uneducated), 20 points (primary education or above), 24 points (secondary education or above). 2. Inclusion criteria of healthy volunteers: (1) Aged 18-80 years, primary school education or above, no gender limit; (2) Han nationality, right-handed; (3) Generally feel that they are in good physical health and have no history of mental or neurological diseases; (4) No other MRI contraindications such as claustrophobia; (5) Normal cognitive function, MMSE>=18 points (uneducated), 20 points (primary school or above culture), 24 points (middle school or above culture).
Exclusion criteria
Exclusion criteria: 1. Exclusion criteria for patients with cerebral hemorrhage: (1) The present disease is accompanied by intracranial infection, intracranial hypertension, severe cerebral edema, continuous deterioration of neurological function, frequent epilepsy; (2) The patient is accompanied by severe cardiopulmonary insufficiency, atrial fibrillation, pulmonary infection, gastrointestinal bleeding, tumor, liver and renal failure, etc.; (3) Patients with present disease accompanied by intracranial infection, brain demyelination disease, and mental illness; (4) Patients with previous or current disease and history of craniocerebral trauma, intracranial tumors, or craniotomy. 2. Exclusion criteria for healthy subjects: (1) A history of stroke, brain tumor, Parkinson's disease, encephalitis, epilepsy, and brain trauma; (2) Abusers of alcohol, drugs or other psychoactive substances; (3) Patients with severe hearing and vision impairment and aphasia who cannot achieve the assessment and cannot complete the study; (4) Patients with a history of severe head trauma; (5) Others considered unsuitable for inclusion by the researchers.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fugl-meyer scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Cortical thickness;Gray matter volume;Mean diffusion kurtosis;Anisotropic fraction;Mean diffusion coefficient;Functional connection;Modified Rankin scale score;Barthel index; | — |
Countries
China
Contacts
Public ContactGong Mingqiang
Shenzhen Hospital of Traditional Chinese Medicine
Outcome results
None listed