Autism Spectrum Disorder (ASD)
Conditions
Interventions
Intervention group:Active transcranial pulsed current stimulation + Standard therapy (ABA, Structured learning , Play therapy , Speech therapy)
Control group:Sham transcranial pulsed current stimulation + Standard therapy ( ABA, Structured learning , Play therapy , Speech therapy)
Sponsors
Nanhai Maternity and Children's Hospital Affiliated to Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
3 Years to 14 Years
Inclusion criteria
Inclusion criteria: 1. Subject meets the DSM-V(American Psychiatric Association, 2013b) diagnostic criteria for autism spectrum disorder. 2. The subject and parent /legal guardian gave informed consent to the treatment, agree to commit to the course of treatment and complete the various pre- and post-treatment assessments. 3. Children aged 3-14 years, regardless of gender. 4. Subjects with IQ score > 35 , according to WISC (4th edition) 5. No history of epilepsy
Exclusion criteria
Exclusion criteria: 1. Those who do not meet the above inclusion criteria; 2. Subjects 14 years old; 3. Subjects with IQ score < 35, Children with severe cognitive impairment, according to WISC (4th edition) 4. Subjects with comorbid epilepsy or history of epileptic disorders or history of brain tumors or traumatic brain injury; 5. Subjects with presence of congenital genetic metabolic disorders and psychiatric disorders such as schizophrenia and psychosis, or a family history of schizophrenia and psychosis. 6. Subjects diagnosed with obstructive sleep apnea. 7. Subjects with skull defect or presence of severe scalp infection at the proposed site of stimulation. 8. Subjects with a history of craniotomy, presence of any ferromagnetic metal or implanted medical devices in the head or body, eg. cochlear implant, pacemaker or defibrillator; 9. Subjects with history of substance abuse or dependence, use of benzodiazepines, neuroleptics and antipsychotic medications including risperidone and haloperidol; 10. Subjects who have current involvement with other forms of non-invasive brain stimulation including transcranial magnetic stimulation or transcranial direct current stimulation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Autism Treatment Evaluation Checklist; | — |
Secondary
| Measure | Time frame |
|---|---|
| Autism Behaviour Checklist;Children's Sleep Habits Questionnaire; | — |
Countries
China
Contacts
Public ContactLiu Zhenhuan
Nanhai Maternity and Children's Hospital Affiliated to Guangzhou University of Chinese Medicine
Outcome results
None listed