Effects of the use of vasoactive drugs in surgery on perioperative neurocognitive disorder: a randomized controlled double-blind trial

Effects of the use of vasoactive drugs in surgery on perioperative neurocognitive disorder: a randomized controlled double-blind trial - Effects of the use of vasoactive drugs in surgery on perioperative neurocognitive disorder

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059109

Enrollment

Unknown

Registered

2022-04-25

Start date

2022-04-15

Completion date

Unknown

Last updated

2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

perioperative neurocognitive disorder

Interventions

two:vasoactive drugs

Eligibility

Sex/Gender

All

Age

40 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Aged 40-90 years, ASA grade I-III; 2. No severe dysfunction of liver and kidney; 3. No history of psychotropic drug addiction; 4. Patients undergoing abdominal surgery.

Exclusion criteria

Exclusion criteria: 1. Central nervous system infection, head trauma, or other obvious neurological diseases; 2. Severe visual and hearing impairment; 3. History of severe mental or neurological diseases, such as Alzheimer's disease, Parkinson's syndrome, cerebrovascular accidents and cerebrovascular diseases; 4. Preoperative Mini Mental State Examination Scale (MMSE) <=23 points; 5. Abuse of drugs or psychotropic substances, long-term use of steroids and hormones; 6. Family history of genetic diseases (such as early onset familial AD, hereditary ataxia, hereditary spastic paraplegia, etc.).

Design outcomes

Primary

Measure	Time frame
perioperative neurocognitive disorder;	—

Countries

China

Contacts

Public ContactBi Yanlin

Qingdao Municipal Hospital

pndable2021@sina.com+86 18661675610

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026