Lung cancer and lung nodules
Conditions
Interventions
Group QB:Intrathecal morphine and bupivacaine
Group Q:Intrathecal morphine
Group B:Intrathecal bupivacaine
Group C:None
Sponsors
Affiliated Hospital of Yangzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Elective thoracoscopic lobectomy was performed in patients aged 18-65 years, no gender limit; 2. ASA Grade I-II, BMI 18-30 kg/m^2; 3. Plan to stay in hospital >= 48 hours after surgery; 4. Be aware of and volunteer for the study.
Exclusion criteria
Exclusion criteria: 1. Patients with severe cardiac, liver and renal dysfunction before surgery; 2. Long-term users of analgesic and sedative drugs and alcoholics; 3. There are infected people at the puncture site; 4. Patients with severe cerebrovascular disease, Alzheimer's disease, epilepsy, Parkinson's disease and other neuropsychiatric diseases; 5. Previous history of intracranial surgery or craniocerebral injury; 6. Severely impaired in vision, hearing, speech, or unable to communicate for other reasons; 7. Those who are allergic to or contraindicated with morphine, local anesthetics and non-steroidal anti-inflammatory drugs (NSAID); 8. Patients with coagulation dysfunction; 9. Patients with bronchial asthma, hypothyroidism, prostatic hypertrophy and dysuria.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| acute pain score;chronic pain score;postoperative recovery index;the incidence of adverse reactions; | — |
Secondary
| Measure | Time frame |
|---|---|
| total opioids; | — |
Countries
China
Contacts
Public ContactZhang Jianyou
Affiliated Hospital of Yangzhou University
Outcome results
None listed