Skip to content

Effect of intestinal preparation based on rapid rehabilitation surgery on intestinal barrier function in patients undergoing surgery for gynecological malignant tumors

Effect of nonmechanical bowel preparation on postoperative recovery in patients with gynecological malignant tumor

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059101
Enrollment
Unknown
Registered
2022-04-25
Start date
2019-09-28
Completion date
Unknown
Last updated
2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gynaecological malignant tumours

Interventions

control group:mechanical bowel preparation before surgery
experimental group:non-mechanical bowel preparation before surgery

Sponsors

Women's Hospital School of Medicine Zhejiang University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 18 to 75 years; 2. Total hysterectomy and pelvic abdominal lymph node dissection were planned; 3. General anesthesia by tracheal intubation; 4. No previous history of abdominal surgery; 5. No history of mental illness; 6. Informed consent and voluntary participation in this study.

Exclusion criteria

Exclusion criteria: 1. Patients who have been assessed by the competent physician as having possible gastrointestinal metastasis of the tumor and the operation may involve the intestine; 2. Patients who cannot tolerate oral intestinal cleansers; 3. Patients who cannot tolerate mechanical enema; 4. Pregnancy; 5. Complicated with severe cardiovascular and cerebrovascular diseases, endocrine diseases, psychosis, chronic intestinal diseases (intestinal tuberculosis, Crohn's disease, chronic non-specific ulcerative colitis, etc.); 6. Acute abdomen (gastrointestinal perforation, gastrointestinal bleeding, intestinal obstruction, intestinal torsion, etc.); 7. Poor compliance, unable to follow the doctor's advice to carry out relevant preparations for rapid rehabilitation.

Design outcomes

Primary

MeasureTime frame
postoperative gastrointestinal function parameters;postoperative gastrointestinal symptoms;plasma concentrations of D-lactate;plasma concentrations of diamine oxidase;

Secondary

MeasureTime frame
intraoperative visual field satisfaction;injuries to anatomical structures;involuntary defecation during surgery;total operation time;length of hospital stay;experience of oral intestinal cleanser in patients with mechanical bowel preparation;wound healing;surgical site infection;

Countries

China

Contacts

Public ContactFeng Suwen

Women's Hospital School of Medicine Zhejiang University

fengsw@zju.edu.cn+86 13957168708

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026