tuberculosis
Conditions
Interventions
Test Group:one-way bronchial valve
Sponsors
The Eighth Medical Center of PLA General Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) Patients aged 16-75, with no gender limitation, sputum AFB-positive re-treatment of cavitary tuberculosis, cavity age> 1 year, and drug susceptibility test results show bacterial resistance or multi-drug resistance; (2) Voluntary participation and Sign informed consent; (3) Those who can establish long-term contacts and can assist in completing regular follow-ups.
Exclusion criteria
Exclusion criteria: (1) Age> 75 years; (2) Accompanied by cardiac insufficiency or severe heart disease such as congenital heart disease, coronary heart disease, rheumatic heart disease, pulmonary heart disease, etc., who cannot bear bronchoscopy interventional therapy; (3) Accompanied by severe heart disease Active pneumonia, hemoptysis, tumor, or severe emphysema, bullae, COPD and other lung diseases that affect the effect of valve placement and respiratory function; (4) Congenital or acquired bronchial deformity, deformation, stenosis, etc. Operators performing valve placement; (5) Caseous pneumonia and other dissolving cavities and cavities dominated by lung consolidation are not included in this study; (6) Accompanied by severe liver and kidney damage, unable to withstand systemic chemotherapy (7) Those who are confirmed or suspected to be infected with mold and other pathogens in the cavity; (8) Those who are expected to be effective in the near future after the adjusted plan.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Chest CT;Sputum smear for acid-fast bacilli;electronic bronchoscopy; | — |
Countries
China
Contacts
Public ContactHuiru An
Outcome results
None listed