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Efficacy of DARLIE toothpaste on extrinsic stain removal

Efficacy of DARLIE toothpaste on extrinsic stain removal

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059076
Enrollment
Unknown
Registered
2022-04-23
Start date
2022-04-25
Completion date
Unknown
Last updated
2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extrinsic stain

Interventions

256 test group:toothpaste 256
356 test group:toothpaste 356
793 control group:toothpaste 793

Sponsors

Sichuan University West China Hospital of Stomatology
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 18-65; 2. Overally healthy; 3. Able to participate follow-up examinations on time; 4. No less than 20 natural teeth without any large-area filling or crown; 5. There is extrinsic stain on tooth surface with Lobene>1.5; 6. Having signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe oral diseases, chronic conditions or being allergic to study products; 2. Fluorosis or tetracycline pigmentation teeth; 3. Late-stage periodontitis; 4. Female in the state of pregnancy or breastfeeding; 5. Having been concurrently enrolled in other clinical trials; 6. In the process of orthodontic treatment; 7. Allergic to toothpaste or oxides; 8. Having bleached their teeth 6 months prior to the study or having their teeth prophylaxed 3 months prior to the study.

Design outcomes

Primary

MeasureTime frame
Lobene Stain Index;

Countries

China

Contacts

Public ContactHong Xiao

West China Hospital of Stomatology, Sichuan University

759293909@qq.com+86 18200232498

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026