Clinical application of nasal high flow oxygen delivery (HFNC) in painless bronchoscopy

To observe whether transnasal high flow oxygen inhalation (HFNC) can improve the oxygenation of patients during painless bronchoscopy under general anesthesia compared with traditional transnasopharyngeal ventilation

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200059069

Enrollment

Unknown

Registered

2022-04-23

Start date

2022-06-01

Completion date

Unknown

Last updated

2024-02-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients undergoing bronchoscopy

Interventions

HFNC group:Transnasal high flow oxygen delivery (HFNC) for painless bronchoscopy

Oxygen inhalation through nasal catheterization:Oxygen inhalation through nasal catheter is used for painless bronchoscopy

Eligibility

Sex/Gender

All

Age

18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients requiring painless bronchoscopy or bronchoscopy ultrasound examination (EBUS); 2. Age: 18-75, no gender limitation; 3. Patients willing to sign informed consent.

Exclusion criteria

Exclusion criteria: 1. Blood oxygen saturation below 90% after entry; 2. Preoperative visit to patients with difficult airway; 3. Patients with nasopharyngeal obstruction, skull base fracture, and presence of nasopharyngeal ventilation or HFNC contraindications; 4. Severe cardiorespiratory and renal dysfunction, severe psychoneurotic or psychological disorders; 5. Pregnant and lactating patients; 6. BMI>30kg/m2 or <18 kg/m2.

Design outcomes

Primary

Measure	Time frame
The incidence of hypoxemia;Incidence of oxygen failure;Minimum oxygen saturation;	—

Secondary

Measure	Time frame
Hemodynamic changes;Sedation score;Adverse reactions;	—

Countries

China

Contacts

Public ContactNanjin Chen

Taizhou Hospital of Zhejiang Province

chennj@enzemed.com+86 13750668783

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026