Subarachnoid hemorrhage
Conditions
Interventions
Treatment group:3% hydrogen inhalation
Control group:Routine oxygen inhalation
Sponsors
Department of Neurosurgery, The Affiliated Drum Tower Hospital, School of Medicine, Nanjing University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patient or entrusted family members voluntarily signed the informed consent for this test; 2. Aged from 20 years to 70 years old, regardless of gender; 3. SAH patients with ruptured aneurysms; 4. Interventional therapy was completed within 72 hours after the aneurysm rupture.
Exclusion criteria
Exclusion criteria: 1. Patients are judged by the responsible physician to be unfit to participate in the study; 2. Patients with severe cardiac insufficiency, pulmonary insufficiency, liver insufficiency, or kidney insufficiency; 3. Patients with massive intracranial hematoma; 4. Patients undergo craniotomy for clipping aneurysms; 5. Patients who reject random grouping; 6. Any reasons for not being selected by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neurological function assessment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brain edema;cerebral vasospasm;Nerve injury marker levels;Oxidative stress level;Inflammation levels;The lactic acid level;Brain electrical activity; | — |
Countries
China
Contacts
Public ContactZong Zhuang
The Affiliated Drum Tower Hospital, School of Medicine, Nanjing University
Outcome results
None listed