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A randomized controlled study on the efficacy and safety of mindfulness-based cognitive therapy in improving anxiety and depression symptoms of bipolar disorder and preventing relapse.

A randomized controlled study on the efficacy and safety of mindfulness-based cognitive therapy in improving anxiety and depression symptoms of bipolar disorder and preventing relapse.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200059040
Enrollment
Unknown
Registered
2022-04-23
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

bipolar disorder

Interventions

Therapy Group:mindfulness-based cognitive therapy
Therapy Group:treatment as usual
Control Group:treatment as usual

Sponsors

Beijing Huilongguan Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Meet the DSM-V diagnostic criteria for bipolar disorder, currently in a state of mild to moderate depression (HAMD-17 >= 7 points and = 14 points), and not in mania or in hypomanic state (YMAS=5 points); 2. Age 18-60 years old, high school education level or above; 3. The patients themselves voluntarily participated in this study and signed the informed consent; 4. Within 12 weeks before screening, the patient's psychiatric drug treatment plan is stable, and the types and doses of psychiatric drugs used within 8 weeks of the planned treatment period do not need to be adjusted.

Exclusion criteria

Exclusion criteria: 1. Suicidal tendencies (with clear suicidal thoughts on mental examination, or suicide in item 3 of HAMD-17 >= 3 points); 2. Currently accompanied by psychotic symptoms; 3. According to DSM-V, diagnosed with substance-related and addictive disorders (excluding tobacco-related disorders) within 6 months before screening; 4. Suffered serious physical or psychological trauma within 3 months; 5. Have attended eight weeks of mindfulness-related courses, including Mindfulness-Based Stress Reduction (MBSR) and MBCT; 6. According to DSM-V, there is a current or past history of any of the following diseases: (1) schizophrenia spectrum and other psychotic disorders; (2) neurodevelopmental disorders; (3) disruptive, impulse control and conduct disorders; cause mental disorders. 7. Uncooperate with treatment, difficult to complete the treatment, or those who think that there are other reasons why the investigator is not suitable to participate in the research project.

Design outcomes

Primary

MeasureTime frame
17-Item Hamilton Rating Scale for Depression;Hamilton Rating Scale for Anxiety;

Secondary

MeasureTime frame
Young's Mania Rating Scale;Connor-Davidson Resilience Scale;Ruminative Responses Scale;the World Health Organization Quality of Life(BREF);The Five Facet Mindfulness Questionnaire;NEO Five-Factor Inventory;Young Schema Questionnaire(Short Form);electrocardiogram;

Countries

China

Contacts

Public ContactYaxue Wu

Beijing Huilongguan Hospital

psywyx@126.com13693141042

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026