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Evaluation of coronary recanalization after thrombolytic therapy for acute myocardial infarction based on metabolomics

Evaluation of coronary recanalization after thrombolytic therapy for acute myocardial infarction based on metabolomics

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200059031
Enrollment
Unknown
Registered
2022-04-23
Start date
2021-09-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infraction

Interventions

Drug thrombolysis recanalization group:None
Drug thrombolysis failed group:None

Sponsors

The 2nd Affiliated Hospital of Harbin Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: 1. Patients older than 18 years old; 2. Acute chest pain lasting more than 30 minutes, but not more than 12 hours; 3. ST-segment elevation in two or more adjacent leads on the ECG is >=0.1mV in limb leads, >=0.2mV in chest leads, or new complete left (or right) bundle branch block; 4. Percutaneous coronary intervention cannot be completed within 120 minutes.

Exclusion criteria

Exclusion criteria: 1. History of intracranial hemorrhage or stroke of unknown location, and ischemic stroke within the past 6 months; 2. Central nervous system injury, nervous system tumor or arteriovenous malformation; 3. Major trauma, surgical operation or head injury in the past 2 months; 4. Gastrointestinal bleeding within the past 1 month, bleeding disorders with known causes (except menstruation); 5. Aortic dissection is definite, highly suspected or cannot be ruled out; 6. Received non-compressible puncture (such as liver biopsy, lumbar puncture) within 24 hours; 7. During oral anticoagulant therapy; 8. 1 week of pregnancy or postpartum; 9. Refractory hypertension [systolic blood pressure>180mmHg and (or) diastolic blood pressure>110mmHg; 10. Suffering from advanced liver disease, infective endocarditis, active peptic ulcer; 11. Prolonged or invasive resuscitation.

Design outcomes

Primary

MeasureTime frame
Coronary imaging features;Serum metabolic profile;

Countries

China

Contacts

Public ContactYan Fang

The 2nd Affiliated Hospital of Harbin Medical University

fangyan5668@163.com+86 13836112917

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026