Corneal burns
Conditions
Interventions
Experimental group:Transplantation of autologous bone marrow mesenchymal stem cells and their derivatives
Sponsors
The First Affiliated Hospital of Army Military Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Sign informed consent voluntarily as the subject. 2. Aged between 18 and 70 years, regardless of gender. 3. Make a clear diagnosis of moderate to severe ocular surface thermal burn and chemical burn. 4. Corrected vision: BCVA<=0.1. 5. Moderate to severe eye surface burns.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating patients. 2. Patients who have undergone corneal transplantation. 3. Incomplete eyelid closure caused by eyelid injury affects the recovery of ocular surface. 4. The recovery of ocular surface is affected by eyelid insufficiency caused by ocular protrusion. 5. Moderate to severe primary diseases of cardiovascular, liver, kidney and hematopoietic system. 6. Combined with mental illness and mental illness. 7. Previous human immunodeficiency virus and other infections. 8. Patients with systemic or topical application of other drugs affecting the evaluation of efficacy. 9. Participated in other clinical trials in the past three months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptoms and eye signs before and after treatment;Evaluation of visual function improvement; | — |
Countries
China
Contacts
Public ContactLiu Yong
The First Affiliated Hospital of Army Military Medical University
Outcome results
None listed