Postoperative delirium
Conditions
Interventions
Control group:PaCO2 was 35-45mmHg
Experimental group:PaCO2 was 46-55mmHg
Sponsors
Department of Anesthesiology, Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Aged >= 65 years, no gender limit; 2. The pathological or cytological diagnosis was esophageal cancer, and thoracoscopic radical operation was planned; 3. ASA disease classification grade II-III; 4. Subjects understood and signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. The score of MMSE scale is less than 24 points; 2. Have a second primary tumor; 3. Complicated with serious diseases, including severe liver and kidney function injury, autoimmune diseases, immune deficiency, cardiovascular and cerebrovascular diseases, neuropsychiatric diseases, blood diseases, etc.; 4. Patients with previous difficulties in endoscopic surgery (such as severe chronic obstructive pulmonary disease, acute inflammatory bowel disease, obesity, etc.); 5. Poor control of diabetes and hypertension; 6. Poor compliance, difficult to cooperate with treatment and follow-up; 7. Participated in other clinical studies in the last 3 months; 8. Situations in which other researchers found it inappropriate to participate in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium;Cerebral oxygen; | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemodynamics;Postoperative pain score; | — |
Countries
China
Contacts
Public ContactHu Xianwen
Outcome results
None listed