hypoxemia
Conditions
Interventions
esketamine group:Intravenous administration of esketamine
sufentanil group:Intravenous administration of sufentanil
Sponsors
Beijing Chao-Yang Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged >=18 years; 2. Selective electronic bronchoscopy; 3. ASA 1-3.
Exclusion criteria
Exclusion criteria: 1. SpO2 after preoperative oxygenation was lower than 90%. 2. Have a history of depression or take antidepressants. 3. History of neuropsychiatric disorders or substance abuse. 4. Unable to cooperate with scale evaluation. 5. Abnormal liver and kidney function. 6. History of hyperthyroidism. 7. Severe adverse reactions, such as intraoperative cardiac arrest and CPR. 8. Severe hypertension, intraocular pressure or intracranial pressure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of intraoperative hypoxemia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Severe intraoperative hypoxemia;Duration of hypoxemia;Hypotension or bradycardia;The number of intraoperative choking coughs and incidence of body movements;Quality of awakening;Delirium;Postoperative nausea and vomiting;Patients satisfaction; | — |
Countries
China
Contacts
Public ContactWu Anshi
Outcome results
None listed