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Effect of transthoracic musce block on early postoperative cognitive impairment after valve replacement under cardiopulmonary bypass

Effect of transthoracic musce block on early postoperative cognitive impairment after valve replacement under cardiopulmonary bypass

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058987
Enrollment
Unknown
Registered
2022-04-21
Start date
2022-04-20
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiac Surgery

Interventions

two:Transverse thoracic machine block

Sponsors

The First Affiliated Hospital of Nanchang University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 80 Years

Inclusion criteria

Inclusion criteria: Sixty patients (ASA grade II ~ III, age = 65 years old, male and female) undergoing valve replacement under general anesthesia under cardiopulmonary bypass were selected. In order to exclude the deviation caused by different operation methods and habits, all patients were from the same group of surgeons. The patients were randomly divided into ultrasound-guided patients Transverse thoracic muscle plane block group (group T) and control group (Group C), with 30 cases in each group. The patients in the two groups were in age and sex There was no significant difference in gender, weight and education level (P > 0.05).

Exclusion criteria

Exclusion criteria: Those who disagree with the implementation of transverse thoracic muscle plane block; ? Preoperative Mini Mental State Examination (MMSE) showed cognitive impairment (preoperative score, illiteracy = 17 points, primary school = 20 points, middle school = 22 points, University = 23 points); ? Preoperative mental illness or long-term use of sedatives or antidepressants; ? The skin at the puncture site is damaged or infected; ? History of allergy to amide local anesthetics; ? Unable to communicate due to hearing or vision impairment; ? Have a history of drug abuse or mental illness; ? Thoracoscopic surgery; Patients with secondary surgery.

Design outcomes

Primary

MeasureTime frame
Cognitive function 7 days after operation;

Countries

China

Contacts

Public ContactZhang Yang
mzzhangyang@126.com13576080494

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026