chronic post-thoracoscopic pain
Conditions
Interventions
Group R:TPVB with 0.4% ropivacaine and perioperative intravenous infusion of normal saline
Group D1:TPVB with 0.4% ropivacaine and perioperative intravenous infusion of 0.5µg/kg/h DEX
Group D2:TPVB with 0.4% ropivacaine and 0.5µg/kg DEX, and perioperative intravenous infusion of normal saline
Group D3:TPVB with 0.4% ropivacaine and 1µg/kg DEX, and perioperative intravenous infusion of normal saline
Sponsors
The Second Hospital of Shandong University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled to undergo thoracoscopic unilateral pulmonary lesion resection (cuneiform/segmental/lobectomy); 2. Aged 18-65 years, gender unlimited; 3. ASA rating is I-III; 4. Participate in the study voluntarily and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. There are contraindications to regional anesthesia; 2. Allergic to experimental drugs or general anesthetics; 3. BMI28kg/m^2; 4. Liver and kidney insufficiency; 5. History of chronic pain or opioid use; 6. Pregnant or lactating patients; 7. Sick sinus syndrome/severe bradycardia (HR<50 beats/min)/atrioventricular block above degree II; 8. Mental or nervous system diseases; 9. History of surgery within the last 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Leeds Neurological Signs and Symptoms Score (LANSS Score); | — |
Secondary
| Measure | Time frame |
|---|---|
| Prince-Henry Pain Score;Visual Analogue Scale Score;Quality of Recovery Questionnaire 15;Cumulative consumption of opioids;Number of rescue analgesia; | — |
Countries
China
Contacts
Public ContactJin Yanwu
The Second Hospital of Shandong University
Outcome results
None listed