Application of goal-directed fluid therapy with low central venous pressure combined with stroke volume variability in laparoscopic partial hepatectomy

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200058960

Enrollment

Unknown

Registered

2022-04-20

Start date

2022-07-11

Completion date

Unknown

Last updated

2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Liver tumors

Interventions

Group A:Central venous pressure (CVP) <=5cmH20, stroke variation (SVV) :7%-12%

Group B:Central venous pressure (CVP) <=5cmH20, stroke variation (SVV) :13%-19%

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years (including 18 and 70 years old); 2. Selective laparoscopic partial hepatectomy; 3. ASA grade I-II patients; 4. Child-Pugh grade of liver function A or B; 5. Patients who agreed to participate in this study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. Intraoperative conversion to laparotomy; 2. Discontinue target-directed fluid therapy during hepatectomy for other reasons; 3. Severe complications occurred during perioperative period.

Design outcomes

Primary

Measure	Time frame
blood loss;liver and kidney function;arterial blood gas;	—

Secondary

Measure	Time frame
central venous pressure;stroke volume variation;	—

Countries

China

Contacts

Public ContactLin Chunshui

lcsnfyy@126.com+86 13802784698

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026