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Randomized clinical trial of the effect of preoperative oral carbohydrate on postoperative delirium among elderly patients undergoing gastrointestinal surgery

Randomized clinical trial of the effect of preoperative oral carbohydrate on postoperative delirium among elderly patients undergoing laparoscopic radical gastrointestinal surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058956
Enrollment
Unknown
Registered
2022-04-20
Start date
2022-05-01
Completion date
Unknown
Last updated
2024-02-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative delirium

Interventions

Experimental group:200ml of carbohydrate drink containing 28g orally 28g before surgery

Sponsors

Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
65 Years to 79 Years

Inclusion criteria

Inclusion criteria: 1. Elective laparoscopic radical gastrointestinal surgery; 2. Aged 65-79 years; 3. ASA grade ? to ?.

Exclusion criteria

Exclusion criteria: 1. Complicated with diabetes, abnormal glucose tolerance and use of drugs that affect insulin sensitivity; 2. Weight loss of more than 10% in the past 6 months; 3. The patient was accompanied by nausea, vomiting, gastroesophageal reflux, gastric emptydisorder, pyloric obstruction, etc.; 4. Complicated with severe brain, heart, lung, liver and kidney diseases; 5. Suspected or confirmed history of alcohol and drug abuse; 6. Patients with a history of Alzheimer's disease, Parkinson's disease, delirium; 7. The evaluation is affected by the inability to communicate with visitors due to serious sensory defects (such as vision and hearing impairment) or other reasons.

Design outcomes

Primary

MeasureTime frame
3-minute delirium diagnostic scale;serum glucagon-like 1;glucose-dependent insulinotropic polypeptide;

Secondary

MeasureTime frame
tumor necrosis factor-a;interleukin-6;C-reactive protein;visual analogue scale;systolic blood pressure;diastolic blood pressure;mean blood pressure;heart rate;

Countries

China

Contacts

Public ContactZuo Youbo

Department of Anesthesiology, Affiliated Hospital of North Sichuan Medical College

442687398@qq.com+86 13808271734

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026